Screening and function studies in immunotoxicity testing
نویسندگان
چکیده
منابع مشابه
New approaches to immunotoxicity testing.
New approaches to immunotoxicity testing are reviewed and discussed. A method of activating T-cells in vivo is presented which circumvents artifacts dur to viability effects encountered with in vitro mitogen assays. The use of adoptive transfer approaches to combine the advantages of in vitro manipulation with in vivo function assays is discussed relative to natural killer cells. The need for a...
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Nanoparticles (NPs) present in the environment and in consumer products can cause immunotoxic effects. The immune system is very complex, and in vivo studies are the gold standard for evaluation. Due to the increased amount of NPs that are being developed, cellular screening assays to decrease the amount of NPs that have to be tested in vivo are highly needed. Effects on the unspecific immune s...
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ژورنال
عنوان ژورنال: Veterinary Quarterly
سال: 1981
ISSN: 0165-2176,1875-5941
DOI: 10.1080/01652176.1981.9693826